Dosage/Direction for Use
Adult: For chronic cases in patients with gout or urate deposition (including a history, or presence of tophus and/or gouty arthritis): Initially, 40 mg once daily. Dose may be increased to 80 mg once daily if serum uric acid is >6 mg/dL after 2 weeks. Alternatively, 80 mg once daily. May increase dose to 120 mg once daily if serum uric acid is >6 mg/dL after 2-4 weeks. Gout flare prophylaxis for at least 6 months with an NSAID or colchicine is recommended at treatment initiation.
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