Description
Contents
Simvastatin
Indications/Uses
Zocor is a medicine usedΒ to lower levels of total cholesterol, βbadβ cholesterol (LDL cholesterol), and fatty substances called triglycerides in the blood. In addition, Zocor raises levels of βgoodβ cholesterol (HDL cholesterol). Zocor is a member of the class of medicines called statins.
Dosage/Direction for Use
Adjustments of dosage, if required, should be made at intervals of not less than 4 weeks, to a maximum of 80 mg/day given as a single dose in the evening. The 80-mg dose is only recommended in patients at high risk for cardiovascular complications who have not achieved treatment goals on lower doses and when the benefits are expected to outweigh the potential risks (see Myopathy/Rhabdomyolysis under PRECAUTIONS).
The recommended usual starting dose is 20-40 mg once a day in the evening.
PATIENTS AT HIGH RISK OF CORONARY HEART DISEASE (CHD) OR WITH EXISTING CHD: The usual starting dose of ZOCOR is 40 mg/day given as a single dose in the evening in patients at high risk of CHD (with or without hyperlipidemia), ie., patients with diabetes, history of stroke or other cerebrovascular disease, peripheral vessel disease, or with existing CHD. Drug therapy can be initiated simultaneously with a standard cholesterol-lowering diet and exercise.
PATIENTS WITH HYPERLIPIDEMIA (WHO ARE NOT IN THE RISK CATEGORIES AS PREVIOUSLY MENTIONED): The patient should be placed on a standard cholesterol-lowering diet before receiving ZOCOR and should continue on this diet during treatment with ZOCOR.
The usual starting dose is 20 mg/day given as a single dose a day in the evening.
The recommended usual starting dose is 20-40 mg once a day in the evening.
PATIENTS AT HIGH RISK OF CORONARY HEART DISEASE (CHD) OR WITH EXISTING CHD: The usual starting dose of ZOCOR is 40 mg/day given as a single dose in the evening in patients at high risk of CHD (with or without hyperlipidemia), ie., patients with diabetes, history of stroke or other cerebrovascular disease, peripheral vessel disease, or with existing CHD. Drug therapy can be initiated simultaneously with a standard cholesterol-lowering diet and exercise.
PATIENTS WITH HYPERLIPIDEMIA (WHO ARE NOT IN THE RISK CATEGORIES AS PREVIOUSLY MENTIONED): The patient should be placed on a standard cholesterol-lowering diet before receiving ZOCOR and should continue on this diet during treatment with ZOCOR.
The usual starting dose is 20 mg/day given as a single dose a day in the evening.
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