It is indicated in amenorrhea, in abnormal uterine bleeding due to hormonal imbalance in the absence of organic pathology, such as submucous fibroids or uterine cancer, and in endometriosis.
Therapy with norethisterone must be adapted to the specific indications and therapeutic response of the individual patient. This dosage schedule assumes the interval between menses to be 28 days.
Amenorrhea, abnormal uterine bleeding due to hormonal imbalance in the absence of organic pathology: 5 to 20 mg norethisterone starting with the fifth day of the menstrual cycle and ending on the 25th day.
Endometriosis: Initial daily dosage of 10mg for two weeks with increments of 5 mg per day every two weeks until 30 mg per day is reached. Therapy may be held at this level for six to nine months or until breakthrough bleeding demands temporary termination.