Description
Contents
Prochlorperazine maleate
Indications and Dosage
Intramuscular
Nausea and vomiting
Nausea and vomiting
Adult: As prochlorperazine mesilate: 12.5 mg given via deep inj, may give further doses via oral admininistration, if necessary. As prochlorperazine edisylate: Initially. 5-10 mg, if necessary, may repeat dose 3-4 hourly. Max: 40 mg daily.
Elderly: Dose reduction may be necessary.
Elderly: Dose reduction may be necessary.
Intramuscular
Mania, Schizophrenia
Adult: As prochlorperazine mesilate: 12.5-25 mg bid or tid given via deep inj. As prochlorperazine edisylate: Initially, 10-20 mg via deep inj, may repeat dose 2-4 hourly, if necessary.
Elderly: Dose reduction may be necessary.
Elderly: Dose reduction may be necessary.
Intravenous
Nausea and vomiting
Adult: As prochlorperazine edisylate: 2.5-10 mg given via slow IV inj or infused at a rate not exceeding 5 mg per minute. Max: 10 mg per dose; 40 mg per day.
Elderly: Dose reduction may be necessary.
Elderly: Dose reduction may be necessary.
Oral
Vertigo
Adult: As prochlorperazine mesylate/maleate: In patient with Meniere’s syndrome, labyrinthitis: 5 mg tid, may increased up to 30 mg daily. Reduced dose gradually to 5-10 mg after several weeks.
Elderly: Dose reduction may be necessary.
Elderly: Dose reduction may be necessary.
Oral
Nausea and vomiting
Adult: As prochlorperazine mesylate/maleate: Prophylaxis: 5-10 mg bid or tid. Treatment: Initially, 20 mg, followed by 10 mg after 2 hours, if necessary.
Child: >1 year >10 kg: 0.25 mg/kg bid or tid.
Elderly: Dose reduction may be necessary.
Child: >1 year >10 kg: 0.25 mg/kg bid or tid.
Elderly: Dose reduction may be necessary.
Oral
Adjunct in severe anxiety disorder
Adult: As prochlorperazine mesylate/maleate: Initially, 15-20 mg daily in divided doses. May increase to Max 40 mg daily if necessary.
Elderly: Dose reduction may be necessary.
Elderly: Dose reduction may be necessary.
Oral
Mania, Schizophrenia
Adult: As prochlorperazine mesylate/maleate: Initially, 12.5 mg bid for 7 days, increased at 4-7 days interval until satisfactory response is achieved. Usual dose: 75-100 mg daily.
Elderly: Dose reduction may be necessary.
Elderly: Dose reduction may be necessary.
Rectal
Severe nausea and vomiting
Adult: 25 mg bid.
Elderly: Dose reduction may be necessary.
Elderly: Dose reduction may be necessary.
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