Metronidazole

Urogenital trichomoniasis in both genders; non-specific vaginitis. Intestinal & extraintestinal amoebiasis; giardiasis. Acute ulcerative gingivitis & dental infection. Anaerobically infected leg ulcers & pressure sores. Treatment & prophylaxis of anaerobic infection.

Prophylaxis against anaerobic infections in abdominal (especially colorectal) & gynaecological surgery Adult400 mg 8 hrly. Childn 7.5 mg/kg 8 hrly. Established anaerobic infection Adult Initially 800 mg, followed by 400 mg 8 hrly. Childn 7.5 mg/kg 8 hrly. Duration: 7 days. Urogenital trichomoniasis Adult & childn >10 yr 200 mg tds for7 daysor 800 mgin the morning & 1,200 mg in the evening for 2 daysor 2 g as single dose for 1 day, childn 7-10 yr 100 mg tds for 7 days, 3-7 yr 100 mg bd for 7 days, 1-3 yr 50 mg tds for 7 days. Bacterial vaginosis Adult & childn >10 yr 400 mg bd for 7 daysor 2 g as single dose for 1 day. Invasive intestinal disease in susceptible subject Adult & childn >10 yr 800 mg tds for 5 days, 7-10 yr 400 mg tds for 5 days, 3-7 yr 200 mg qds for 5 days, 1-3 yr 200 mg tds for 5 days. Intestinal disease in less susceptible subjects & chronic amoebic hepatitis Adult & childn >10 yr 400 mg tds for 5-10 days, 7-10 yr 200 mg tds for 5-10 days,3-7 yr 100 mg qds for 5-10 days, 1-3 yr 100 mg tds for 5-10 days. Amoebic liver abscess Duration: 5 days. Symptomless cyst passers Adult & childn >10 yr 400-800 mg tds for 5-10 days,7-10 yr 200-400 mg tds for 5-10 days, 3-7 yr 100-200 mg qds for 5-10 days, 1-3 yr 100-200 mg tds for 5-10 days. Giardiasis Adult & childn >10 yr 2 g once daily for 3 days, 7-10 yr 1 g once daily for 3 days; 3-7 yr 600-800 mg once daily for 3 days, 1-3 yr 500 mg once daily for 3 days. Acute ulcerative gingivitisAdult & childn >10 yr 200 mg tds for 3 days, 7-10 yr 100 mg tds for 3 days, 3-7 yr 100 mg bd for 3 days, 1-3 yr 50 mg tds for 3 days. Acute dental infectionAdult & childn >10 yr200 mg tds for 3-7 days. Leg ulcers & pressure soresAdult & childn >10 yr 400 mg tds for 7 days.