Description
Contents
Metronidazole
Indications/Uses
Urogenital trichomoniasis in both genders; non-specific vaginitis. Intestinal & extraintestinal amoebiasis; giardiasis. Acute ulcerative gingivitis & dental infection. Anaerobically infected leg ulcers & pressure sores. Treatment & prophylaxis of anaerobic infection.
Dosage/Direction for Use
Prophylaxis against anaerobic infections in abdominal (especially colorectal) & gynaecological surgeryΒ Adult400 mg 8 hrly.Β ChildnΒ 7.5 mg/kg 8 hrly.Β Established anaerobic infectionΒ AdultΒ Initially 800 mg, followed by 400 mg 8 hrly.Β ChildnΒ 7.5 mg/kg 8 hrly. Duration: 7 days.Β Urogenital trichomoniasisΒ Adult & childn >10 yrΒ 200 mg tds for7 daysor 800 mgin the morning & 1,200 mg in the evening for 2 daysor 2 g as single dose for 1 day,Β childn 7-10 yrΒ 100 mg tds for 7 days,Β 3-7 yrΒ 100 mg bd for 7 days,Β 1-3 yrΒ 50 mg tds for 7 days.Β Bacterial vaginosisΒ Adult & childn >10 yrΒ 400 mg bd for 7 daysor 2 g as single dose for 1 day.Β Invasive intestinal disease in susceptible subjectΒ Adult & childn >10 yrΒ 800 mg tds for 5 days,Β 7-10 yrΒ 400 mg tds for 5 days,Β 3-7 yrΒ 200 mg qds for 5 days,Β 1-3 yrΒ 200 mg tds for 5 days.Β Intestinal disease in less susceptible subjects & chronic amoebic hepatitisΒ Adult & childn >10 yrΒ 400 mg tds for 5-10 days,Β 7-10 yrΒ 200 mg tds for 5-10 days,3-7 yrΒ 100 mg qds for 5-10 days,Β 1-3 yrΒ 100 mg tds for 5-10 days.Β Amoebic liver abscessΒ Duration: 5 days.Β Symptomless cyst passersΒ Adult & childn >10 yrΒ 400-800 mg tds for 5-10 days,7-10 yrΒ 200-400 mg tds for 5-10 days,Β 3-7 yrΒ 100-200 mg qds for 5-10 days,Β 1-3 yrΒ 100-200 mg tds for 5-10 days.Β GiardiasisΒ Adult & childn >10 yrΒ 2 g once daily for 3 days,Β 7-10 yrΒ 1 g once daily for 3 days;Β 3-7 yrΒ 600-800 mg once daily for 3 days,Β 1-3 yrΒ 500 mg once daily for 3 days.Β Acute ulcerative gingivitisAdult & childn >10 yrΒ 200 mg tds for 3 days,Β 7-10 yrΒ 100 mg tds for 3 days,Β 3-7 yrΒ 100 mg bd for 3 days,Β 1-3 yrΒ 50 mg tds for 3 days.Β Acute dental infectionAdult & childn >10 yr200 mg tds for 3-7 days.Β Leg ulcers & pressure soresAdult & childn >10 yrΒ 400 mg tds for 7 days.
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