Indications and Dosage
Benign gastric ulcer, Duodenal ulcer
Child: 6 months to 11 years Initially, 2 mg/kg or 2.5 mg/kg (Max: 50 mg) via slow IV inj over 10 minutes (either with a syringe pump followed by a 3 mL flush with NaCl 0.9% over 5 minutes or after dilution with NaCl 0.9% to 20 mL). Maintenance of pH >4: 1.5 mg/kg 6-8 hourly via intermittent IV infusion. Alternatively, 0.45 mg/kg via slow IV inj over 2 minutes as loading dose followed by 0.15 mg/kg/hour via continuous IV infusion; ≥12 years Same as adult dose.
Prophylaxis of acid aspiration during general anaesthesia
Prophylaxis of gastrointestinal haemorrhage from stress ulceration