Description
Contents
Ranitidine
Indications and Dosage
Intramuscular, Intravenous
Hypersecretory conditions
Adult: For the treatment of pathological conditions such as Zollinger-Ellison syndrome: 50 mg via IM or slow IV inj over 2 minutes or via intermittent IV infusion at a rate of 25 mg/hour for 2 hours. Dose may be repeated 6-8 hourly.
Intramuscular, Intravenous
Benign gastric ulcer, Duodenal ulcer
Adult: 50 mg via IM or slow IV inj over 2 minutes or via intermittent IV infusion at a rate of 25 mg/hour for 2 hours. Dose may be repeated 6-8 hourly.
Child: 6 months to 11 years Initially, 2 mg/kg or 2.5 mg/kg (Max: 50 mg) via slow IV inj over 10 minutes (either with a syringe pump followed by a 3 mL flush with NaCl 0.9% over 5 minutes or after dilution with NaCl 0.9% to 20 mL). Maintenance of pH >4: 1.5 mg/kg 6-8 hourly via intermittent IV infusion. Alternatively, 0.45 mg/kg via slow IV inj over 2 minutes as loading dose followed by 0.15 mg/kg/hour via continuous IV infusion; ≥12 years Same as adult dose.
Child: 6 months to 11 years Initially, 2 mg/kg or 2.5 mg/kg (Max: 50 mg) via slow IV inj over 10 minutes (either with a syringe pump followed by a 3 mL flush with NaCl 0.9% over 5 minutes or after dilution with NaCl 0.9% to 20 mL). Maintenance of pH >4: 1.5 mg/kg 6-8 hourly via intermittent IV infusion. Alternatively, 0.45 mg/kg via slow IV inj over 2 minutes as loading dose followed by 0.15 mg/kg/hour via continuous IV infusion; ≥12 years Same as adult dose.
Intramuscular, Intravenous
Prophylaxis of acid aspiration during general anaesthesia
Adult: 50 mg via IM or slow IV inj 45-60 minutes prior to induction of anaesthesia.
Intravenous
Prophylaxis of gastrointestinal haemorrhage from stress ulceration
Adult: 50 mg via slow IV inj as a priming dose, followed by 0.125-0.25 mg/kg/hour via continuous infusion. Continue treatment until oral feeding commences.
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